Nutrigenomics Accuracy

Global Precision Wellness

DNA Test Disclaimer - Nutrigenomics

This test is intended solely to provide insights into your body’s ability to metabolize or respond to certain nutrients based on your genetic makeup. It does not evaluate medical conditions, genetic disorders, or disease risk.

The list of genetic variants that are detectable in the assay is outlined below, but is not limited to:

Gene Names Variant (rs ID)

ABCG2

g.88131171G>T

ADRB3

g.37966280A>G

AGT

g.230710048A>G

ALDH2

g.111803962G>A

APOA2

g.161223893G>A

BCO1

g.81230992T>G, g.81268089A>T, g.81280891C>T

CD36

g.80672184G>A

CLYBL

g.99866380C>T

CSTA

g.122329797A>G

CYP1A2

g.74749576C>A

CYP2R1

g.14893332A>G

CYP4F2

g.15879621C>T

DCDC1

g.30738788T>C

DMGDH

g.79020653C>T

ELOVL2

g.10982740T>C

FADS1

g.61803876C>G

FTO

g.53782363C>A

GC

g.71752617A>C

GSTM1

Deletion

GSTT1

Deletion

HFE

g.26090951C>G

HLA-DQ2

g.32445540G>T

HNRNPA1P48

g.51576036G>A

IP6K3

g.33738702C>T

IRAK1BP1

g.78846449T>C

MC4R

g.60183864T>C

MCM6

g.135851076G>A

MS4A3

g.60069719C>T

MTHFR

g.11794419T>G, g.11796321G>A

MUC1

g.155192276C>T

NADSYN1

g.71456403G>T

NBPF3

g.21459575C>T, g.21496799C>T

NPC1L1

g.44525136T>C

NQO1

g.69711242G>A

PPARG2

g.12351626C>G

PRELID2

g.145659268T>C

RPS20P12

g.234394166C>T

SCARB1

g.124822507G>A

SLC23A1

g.139379813C>T

SLC30A8

g.117172544C>T, g.117173494A>G

SOD2

g.159692840A>G

TCF7L2

g.113049143G>T

TF

g.133765185G>A

TMEM258

g.61792609G>A

TRPM6

g.74884880T>C

VKORC1

g.31096368C>T

ZBED3-AS1

g.77129124G>A

ZNF259

g.116778201G>C

The results presented in this report are offered as a supplementary tool to aid in understanding an individual’s nutrient metabolism, tolerance, and response, and are intended for use by healthcare professionals such as dietitians and nutritionists.

These results may support the application of medical nutrition therapy for personalized recommendations and the development of effective health management plans aimed at preventing or managing diet-related chronic diseases and conditions.

This test is not intended to serve as a sole source of information or as a substitute for professional medical advice, diagnosis, or treatment. The ordering physician or healthcare provider is responsible for the diagnosis and management of disease and for determining the most appropriate course of treatment for each patient, based on the data provided.

Adherence to dietary recommendations provided in this report does not guarantee a successful medical outcome. Please consult your healthcare provider for all medical advice. Results are dependent on adequate specimen collection and processing.

The Service Provider will not be held liable for any direct, indirect, special, consequential, exemplary, punitive, or other damages arising from the use or interpretation of the information and/or services contained within this report. If you have any questions about this report or wish to speak with one of Global Precision Diagnostics’ (GPD) representatives, please contact us through our website.

Limitations

A

This assay only detects specific loci genetic variants available in the array. Mosaicism cannot be detected with this assay. Variants that are not included in the assay may be present in the individual and may affect the reported detected variants accuracy. Accuracy and reliability for the assays are >99%.

The test results do not include all new variants/genes associated with nutrient metabolism for which no scientific evidence currently exists.

Nutrigenomic insights are limited to existing scientific research, which continues to evolve. GPD reserves the right to update the list of reportable variants periodically as clinical knowledge and guidelines advance.

B

Nutrigenomics test identifies the genetic variations that may influence how individuals metabolize and respond to certain nutrients. However, food tolerance, nutrient metabolism, body composition, eating habits, dietary requirements and overall nutrient response are also influenced by non-genetic factors such as lifestyle, environment, comorbidities, food-drug interactions, concurrent therapies.

This test does not measure actual nutrient levels in the body; additional laboratory tests (e.g., blood or urine analysis) may be required to assess the current nutritional status. The test cannot predict food allergies and/or other immune-mediated reactions.

C

The results derived from recipient blood sample after bone marrow transplants and/or liver transplants will not be applicable due to interference with this test. Genotyping error chances cannot be excluded completely.

Future research may reveal changes in the interpretation of previously obtained genetic testing results as this test result is based upon current information, development and testing techniques. GPD will notify you of any amendments or modifications in the report or results through the PreciseEHR mobile application.

Methodology

A

Genomic DNA is extracted from dry buccal swabs or whole blood using magnetic particle processing or spin column processing. DNA from individual samples is amplified, and positive controls are used with each run. Both individual samples and positive controls are screened using the Genome Wide Technology.

Data are analysed for the presence or absence of single nucleotide base changes, insertions, deletions, and copy number variants to confirm gene duplication and deletions.

B

Genetic testing was performed in the Molecular Diagnosis Laboratory of Global Precision Diagnostics Sdn. Bhd. at No. 1, Jalan 215, Off, Jalan Templer, Section 51, 46050 Petaling Jaya, Selangor. 

DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer, Nutrigenomics Accuracy – DNA Test Disclaimer.

Clinical Relevance of Nutrigenomics, Clinical Relevance of Nutrigenomics, Clinical Relevance of Nutrigenomics, Clinical Relevance of Nutrigenomics, Clinical Relevance of Nutrigenomics, Clinical Relevance of Nutrigenomics, Clinical Relevance of Nutrigenomics, 

Nutrigenomics Accuracy - DNA Test Disclaimer - Nutrigenomics