Thyroiditis is the swelling (inflammation) of the thyroid gland. The thyroid is a butterfly-shaped gland in the neck that produces hormones controlling growth, metabolism, heart rate and body temperature.
When the thyroid becomes inflamed, it can release either too many or too few hormones, leading to temporary thyrotoxicosis or hypothyroidism.[1][2]
The Three Phases of Thyroiditis
- Thyrotoxic phase: The swollen thyroid releases excess hormones, causing temporary thyrotoxicosis.
- Hypothyroid phase: After weeks or months, hormone stores become depleted, leading to hypothyroidism.
- Euthyroid phase: Thyroid hormone levels return to normal. This may occur temporarily or at the end of the condition.[3]
Symptoms of Thyroiditis
Symptoms of Thyrotoxicosis (Too Much Hormone)
- Anxiety and irritability
- Insomnia
- Palpitations (fast heart rate)
- Fatigue
- Unexplained weight loss
- Muscle weakness
- Heat intolerance
Symptoms of Hypothyroidism (Too Little Hormone)
- Fatigue and poor exercise tolerance
- Weight gain
- Constipation
- Dry skin
- Depression
- Muscle aches
- Cold intolerance
What Causes Thyroiditis?
Thyroiditis can be triggered by viral or bacterial infections, certain medications (such as interferon or lithium), autoimmune reactions, or postpartum changes. Environmental pollutants and occupational exposure may also increase risk.[3][4]
Types of Thyroiditis
- Hashimoto’s thyroiditis — The most common autoimmune form. The immune system attacks the thyroid until it can no longer produce enough hormones.
- De Quervain’s (subacute) thyroiditis — Painful swelling usually triggered by a viral infection such as mumps or flu.
- Postpartum thyroiditis — An autoimmune condition that occurs within one year after childbirth.
- Silent (painless) thyroiditis — Similar to postpartum thyroiditis but can affect both men and women.
- Drug-induced thyroiditis — Caused by medications such as amiodarone, lithium or interferons.
- Radiation-induced thyroiditis — Results from radiation therapy or radioactive iodine treatment.
- Acute (infectious) thyroiditis — Rare and usually caused by bacterial infection.
- Riedel thyroiditis — A rare form involving chronic inflammation and fibrosis of the thyroid.[1][2][3]
How Thyroiditis Is Diagnosed
- Blood tests — Thyroid function tests measure hormone levels.
- Thyroid ultrasound — Evaluates the structure and density of the gland.
- Thyroid scan — Uses radioactive iodine to create images of the thyroid.
- Erythrocyte sedimentation rate (ESR) — Measures inflammation.
- Radioactive iodine uptake test (RAIU) — Assesses how much iodine the thyroid absorbs.[1][3][5]
Treatment Options
Treatment depends on the type and symptoms of thyroiditis. Medications are commonly prescribed. Some cases may require surgery or radioactive iodine therapy.[1][5]
Ways to Support Thyroid Health
- Follow a balanced diet with plenty of fruits, vegetables, whole grains, lean proteins and healthy fats.
- Ensure adequate selenium intake — selenium supports thyroid hormone production and metabolism.
- Consume sufficient iodine, but avoid excessive amounts which can disrupt thyroid function.
- Maintain adequate iron levels, as iron works with selenium and iodine for optimal thyroid hormone synthesis.
- Quit smoking and limit alcohol consumption to reduce the risk of thyroid disease.[6][8][9][10][11][12]
References
- Cleveland Clinic. Thyroiditis: Types, Causes, Symptoms, Diagnosis & Treatment.
- NHS. Thyroiditis.
- WebMD. What is Thyroiditis?
- Benvenga S, et al. Endocrine disruptors and thyroid autoimmunity. Best Pract Res Clin Endocrinol Metab. 2020.
- Endocrine Web. Thyroiditis: Definitions, Causes and Treatments.
- British Thyroid Foundation. Thyroid and diet factsheet.
- Cleveland Clinic. Foods to avoid if you have thyroid issues.
- Premier Heart and Vascular Center. Prevention and treatment of thyroid diseases for heart health.
- Köhrle J. Selenium and the thyroid. Curr Opin Endocrinol Diabetes Obes. 2015.
- Leung AM, Braverman LE. Consequences of excess iodine. Nat Rev Endocrinol. 2014.
- Gruppen EG, et al. Cigarette smoking is associated with higher thyroid hormone and lower TSH levels. Endocrine. 2020.
- Azizi F, et al. Primordial and Primary Preventions of Thyroid Disease. Int J Endocrinol Metab. 2017.

